PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2025245472A1

AssigneeRemix Therapeutics

TitleCompounds and related methods useful for degradation of cyclin k and inhibition of cyclin dependent kinases

Family ID97796201

Family members1

Filing year2025

Publication date2025-11-27

JurisdictionWO

Compounds78

Activity records349

Assays6

Activity compounds and values

Activity records

349 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
GI50	-	<	1000	nM	-	—	CCNK	-	VCaP	PGDB_A007095	PGDB_C012041	PGDB_AS001027	View
GI50	-	<	1000	nM	-	—	CCNK	-	LNCaP	PGDB_A007217	PGDB_C012025	PGDB_AS002467	View
DC50	-	<	500	nM	-	—	CCNK	-	-	PGDB_A007298	PGDB_C012027	PGDB_AS001864	View
GI50	-	<	1000	nM	-	—	CCNK	-	VCaP	PGDB_A007408	PGDB_C011998	PGDB_AS001027	View
GI50	-	>	3000	nM	-	—	CCNK	-	K562	PGDB_A007844	PGDB_C011978	PGDB_AS000413	View
GI50	-	<	1000	nM	-	—	CCNK	-	VCaP	PGDB_A008155	PGDB_C011987	PGDB_AS001027	View
GI50	-	>	3000	nM	-	—	CCNK	-	SH-SY5Y	PGDB_A008237	PGDB_C012002	PGDB_AS000261	View
DC50	-	<	500	nM	-	—	CCNK	-	-	PGDB_A008282	PGDB_C011995	PGDB_AS001864	View
DC50	-	<	500	nM	-	—	CCNK	-	-	PGDB_A008842	PGDB_C011987	PGDB_AS001864	View
GI50	-	<	1000	nM	-	—	CCNK	-	K562	PGDB_A008850	PGDB_C011990	PGDB_AS000413	View
GI50	-	>	3000	nM	-	—	CCNK	-	SH-SY5Y	PGDB_A009079	PGDB_C012000	PGDB_AS000261	View
GI50	-	<	1000	nM	-	—	CCNK	-	K562	PGDB_A009394	PGDB_C012019	PGDB_AS000413	View
DC50	-	<	500	nM	-	—	CCNK	-	-	PGDB_A009572	PGDB_C012021	PGDB_AS001864	View
DC50	-	<	500	nM	-	—	CCNK	-	-	PGDB_A009590	PGDB_C011992	PGDB_AS001864	View
GI50	-	>	3000	nM	-	—	CCNK	-	THP-1	PGDB_A010301	PGDB_C012006	PGDB_AS002373	View
GI50	-	<	1000	nM	-	—	CCNK	-	VCaP	PGDB_A010330	PGDB_C012016	PGDB_AS001027	View
GI50	-	>	3000	nM	-	—	CCNK	-	THP-1	PGDB_A010539	PGDB_C012014	PGDB_AS002373	View
GI50	-	<	1000	nM	-	—	CCNK	-	THP-1	PGDB_A010681	PGDB_C011998	PGDB_AS002373	View
GI50	-	<	1000	nM	-	—	CCNK	-	K562	PGDB_A010822	PGDB_C012024	PGDB_AS000413	View
GI50	-	>	3000	nM	-	—	CCNK	-	K562	PGDB_A010850	PGDB_C011972	PGDB_AS000413	View

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