Activity record

PGDB_A008864

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 10-50 uM

TargetGSPT1
E3 ligaseCRBN
Cell lineKG-1
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001194
PatentCN118234721A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019819
Compound IDPGDB_C019819
Compound化合物 35
Source record IDPGDB_C001231
InChIKeyGVFLLMKGZSHGAL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001194
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
TargetGSPT1
E3CRBN
Cell lineKG-1

Source evidence

Patent IDCN118234721A
Compound location

化合物 35

化合物 35 enlarged structure化合物 35 location on patent page 36
Activity table
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