Activity record

PGDB_A009512

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

Dmax = 96.9 %

TargetIKZF1
Cell lineHT-1080
ConcentrationConcentration series: 0.316 nM, 10 uM
Time20 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002293
PatentEP4393915A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007564
Compound IDPGDB_C007564
Compound化合物 20
Source record IDPGDB_C007564
InChIKeyVGYLUWYHUSGMPW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002293
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration series: 0.316 nM, 10 uM
Treatment time20 h
TargetIKZF1
E3Not specified
Cell lineHT-1080

Source evidence

Patent IDEP4393915A1
Compound location

化合物 20

化合物 20 enlarged structure化合物 20 location on patent page 114
Activity table
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