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Patent
EP4393915A1
24 compounds111 activity records14 assays
Patent summary
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | DC50 | - | = | 0.117 | uM | - | — | SALL4 | - | HT-1080 | PGDB_A007586 | PGDB_C007543 | PGDB_AS000384 | View |
 | DC50 | - | = | 0.002 | uM | - | — | SALL4 | - | HT-1080 | PGDB_A008520 | PGDB_C007558 | PGDB_AS002491 | View |
 | DC50 | - | = | 0.001 | uM | - | — | SALL4 | - | HT-1080 | PGDB_A008824 | PGDB_C007546 | PGDB_AS000384 | View |
 | Dmax | - | = | 96.9 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | - | HT-1080 | PGDB_A009512 | PGDB_C007564 | PGDB_AS002293 | View |
 | Dmax | - | = | 45.4 | % | Concentration context: HiBiT SALL4:_D max (%) | 20 h | SALL4 | - | HT-1080 | PGDB_A009653 | PGDB_C007549 | PGDB_AS001879 | View |
| Dmax | - | = | 57.4 | % | Concentration context: HiBiT SALL4:_D max (%) | 20 h | SALL4 | - | HT-1080 | PGDB_A010303 | PGDB_C007543 | PGDB_AS001879 | View |
 | Dmax | - | = | 92.2 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | - | HT-1080 | PGDB_A010940 | PGDB_C007560 | PGDB_AS002293 | View |
 | DC50 | - | > | 10 | uM | - | — | SALL4 | - | HT-1080 | PGDB_A012437 | PGDB_C007557 | PGDB_AS000384 | View |
 | Dmax | - | = | 93.1 | % | - | 20 h | IKZF1 | - | HT-1080 | PGDB_A012487 | PGDB_C007552 | PGDB_AS000825 | View |
 | DC50 | - | > | 10 | uM | - | — | SALL4 | - | HT-1080 | PGDB_A013230 | PGDB_C007559 | PGDB_AS002491 | View |
| Dmax | - | = | 79.3 | % | Concentration context: HiBiT SALL4: D max (%) | 20 h | SALL4 | - | HT-1080 | PGDB_A013319 | PGDB_C007558 | PGDB_AS000801 | View |
| DC50 | - | = | 0.23 | nM | - | — | IKZF1 | - | HT-1080 | PGDB_A014100 | PGDB_C007552 | PGDB_AS001653 | View |
 | Dmax | - | = | 93.5 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | - | HT-1080 | PGDB_A014758 | PGDB_C007563 | PGDB_AS002293 | View |
 | DC50 | - | = | 5.89 | nM | - | — | IKZF1 | - | HT-1080 | PGDB_A015086 | PGDB_C007556 | PGDB_AS001653 | View |
 | DC50 | - | = | 0.017 | nM | - | — | IKZF1 | - | HT-1080 | PGDB_A015094 | PGDB_C007547 | PGDB_AS001653 | View |
 | Dmax | - | = | 95.5 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | - | HT-1080 | PGDB_A015547 | PGDB_C005650 | PGDB_AS002293 | View |
 | Dmax | - | = | 91.8 | % | Concentration context: HiBiT IKZF1:_D max (%) | 20 h | IKZF1 | - | HT-1080 | PGDB_A015647 | PGDB_C007544 | PGDB_AS001371 | View |
 | Dmax | - | = | 96.1 | % | Concentration series: 0.316 nM, 10 uM | 20 h | IKZF1 | - | HT-1080 | PGDB_A016191 | PGDB_C007562 | PGDB_AS002293 | View |
| DC50 | - | = | 0.105 | nM | - | — | IKZF1 | - | HT-1080 | PGDB_A016602 | PGDB_C005650 | PGDB_AS002064 | View |
| Dmax | - | = | 69.3 | % | Concentration context: HiBiT IKZF1:_D max (%) | 20 h | IKZF1 | - | HT-1080 | PGDB_A016626 | PGDB_C007556 | PGDB_AS001371 | View |