Activity record

PGDB_A010112

Assay: bindingQC: ambiguous
Activity overview

IC50 = 60 nM

Cell line293T.116
Time2 h
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS001204
PatentWO2022081927A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C026760
Compound IDPGDB_C026760
Compound225
Source record IDPGDB_C026760
InChIKeyKHYMYDSCORGUFO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001204
Assay familybinding
Assay systemcell_based
ReadoutIC50
Treatment time2 h
TargetCRBN
E3CRBN
Cell line293T.116
OrganismHomo sapiens

Source evidence

Patent IDWO2022081927A1
Compound location

225

225 enlarged structure225 location on patent page 525
Activity table
Page 525 · table single