PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2022081927A1

AssigneeC4 Therapeutics

Family members12

Filing year2,021

JurisdictionWO

Compounds35

Activity records182

Assays12

Activity compounds and values

Activity records

182 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	>	10000	nM	-	—	-	-	NCI-H929.11	PGDB_A007086	PGDB_C016632	PGDB_AS000877	View
Emax	-	<	45	%	-	DC50 > 10000 nM \| DC50 >= 100 nM and <= 1000 nM \| DC50 < 100 nM	-	-	NCI-H929.11	PGDB_A007170	PGDB_C016633	PGDB_AS001790	View
DC50	-	>	10000	nM	-	—	-	-	NCI-H929.11	PGDB_A007258	PGDB_C026783	PGDB_AS000877	View
Emax	-	>=	45	%	-	DC50 > 10000 nM \| > 100 nM \| DC50 < 100 nM	-	-	293T.114	PGDB_A007521	PGDB_C016636	PGDB_AS000287	View
Emax	-	>	60	%	-	DC50 > 10000 nM \| DC50 >= 100 nM and <= 1000 nM \| > 100 nM	-	-	KELLY.2	PGDB_A007789	PGDB_C016648	PGDB_AS000499	View
Emax	-	>=	45	%	-	DC50 > 10000 nM \| DC50 >= 100 nM and <= 1000 nM \| DC50 < 100 nM	-	-	NCI-H929.11	PGDB_A008459	PGDB_C016645	PGDB_AS001790	View
Emax	-	>	60	%	-	DC50 > 10000 nM \| > 100 nM \| DC50 < 100 nM	-	-	293T.114	PGDB_A009296	PGDB_C016638	PGDB_AS000287	View
Emax	-	>	60	%	-	DC50 > 10000 nM \| > 100 nM \| DC50 < 100 nM	-	-	293T.114	PGDB_A009578	PGDB_C016642	PGDB_AS000287	View
Emax	-	>	60	%	-	DC50 > 10000 nM \| DC50 >= 100 nM and <= 1000 nM \| > 100 nM	-	-	KELLY.2	PGDB_A010004	PGDB_C016650	PGDB_AS000499	View
IC50	-	=	60	nM	-	—	-	-	293T.116	PGDB_A010112	PGDB_C026760	PGDB_AS001204	View
Emax	-	>	60	%	-	DC50 > 10000 nM	-	-	293T.114	PGDB_A010271	PGDB_C016648	PGDB_AS000364	View
DC50	-	>	10000	nM	-	—	-	-	NCI-H929.11	PGDB_A010319	PGDB_C026791	PGDB_AS000877	View
DC50	-	>	10000	nM	-	—	-	-	NCI-H929.11	PGDB_A011306	PGDB_C016634	PGDB_AS000877	View
DC50	-	>	10000	nM	-	—	-	-	293T.114	PGDB_A011907	PGDB_C016638	PGDB_AS001223	View
Emax	-	>	60	%	-	DC50 > 10000 nM \| > 100 nM \| DC50 < 100 nM	-	-	293T.114	PGDB_A012033	PGDB_C026783	PGDB_AS000287	View
DC50	-	<	100	nM	-	—	-	-	KELLY.2	PGDB_A012931	PGDB_C016652	PGDB_AS001296	View
DC50	-	<	100	nM	-	—	-	-	NCI-H929.11	PGDB_A013043	PGDB_C026764	PGDB_AS000877	View
Emax	-	<	45	%	-	DC50 > 10000 nM \| DC50 >= 100 nM and <= 1000 nM \| DC50 < 100 nM	-	-	NCI-H929.11	PGDB_A013068	PGDB_C025110	PGDB_AS001790	View
Emax	-	<	45	%	-	DC50 > 10000 nM \| DC50 >= 100 nM and <= 1000 nM \| DC50 < 100 nM	-	-	NCI-H929.11	PGDB_A013184	PGDB_C016646	PGDB_AS001790	View
Emax	-	>=	45	%	-	DC50 > 10000 nM \| DC50 >= 100 nM and <= 1000 nM \| > 100 nM	-	-	KELLY.2	PGDB_A013600	PGDB_C016637	PGDB_AS000499	View

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