Activity record

PGDB_A010468

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 30-40 %

TargetIKZF3
Cell lineRPMI-8226
Concentration10 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS000859
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024249
Compound IDPGDB_C024249
CompoundGT-10492
Source record IDPGDB_C024249
InChIKeyYRXFDCQNONQUOQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000859
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineRPMI-8226
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10492

GT-10492 enlarged structureGT-10492 location on patent page 26
Activity table
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