Activity record

PGDB_A011141

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetGSPT1
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001361
PatentCN120441535A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001525
Compound IDPGDB_C001525
Compound2;实施例2
Source record IDPGDB_C001525
InChIKeyKJYMHUZNFUDWOR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001361
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDCN120441535A
Compound location

2;实施例2

2;实施例2 enlarged structure2;实施例2 location on patent page 47
Activity table
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