Activity record

PGDB_A011830

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 >= 1000 nM

TargetGSPT1
Cell lineKG-1
Time72 h
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000854
PatentWO2024251301A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007921
Compound IDPGDB_C007921
CompoundCX-1
Source record IDPGDB_C007921
InChIKeyHOGAYZZVBRZZLU-ZXVVBBHZSA-N

Assay context

Assay IDPGDB_AS000854
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineKG-1

Source evidence

Patent IDWO2024251301A1
Compound location

CX-1

CX-1 enlarged structureCX-1 location on patent page 16
Activity table
Page 20 · table single