Activity record

PGDB_A012209

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 > 100 uM

TargetCRBN
E3 ligaseCRBN
Time10 min
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS002439
PatentUS12540127B2
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009036
Compound IDPGDB_C009036
CompoundI-3;I-3;I-3
Source record IDPGDB_C009036
InChIKeyMHJRQTYKWMYTQA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002439
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time10 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDUS12540127B2
Compound location

I-3;I-3;I-3

I-3;I-3;I-3 enlarged structureI-3;I-3;I-3 location on patent page 51
Activity table
Page 176 · table single