PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberUS12540127B2

AssigneeKymera Therapeutics

TitleCRBN ligands and uses thereof

Family ID65810613

Family members7

Filing year2022

Publication date2026-02-03

JurisdictionUS

Compounds31

Activity records35

Assays3

Activity compounds and values

Activity records

35 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	>	100	uM	-	—	CRBN	CRBN	-	PGDB_A012209	PGDB_C009036	PGDB_AS002439	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A012655	PGDB_C009038	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A013802	PGDB_C009034	PGDB_AS001130	View
IC50	-	=	1-10	uM	-	—	CRBN	CRBN	-	PGDB_A015418	PGDB_C009047	PGDB_AS001130	View
IC50	-	=	10-100	uM	-	—	CRBN	CRBN	-	PGDB_A018755	PGDB_C009037	PGDB_AS002439	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A024195	PGDB_C009035	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A024343	PGDB_C009039	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A027283	PGDB_C009051	PGDB_AS001130	View
IC50	-	=	10-100	uM	-	—	CRBN	CRBN	-	PGDB_A028686	PGDB_C009036	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A031399	PGDB_C009057	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A038440	PGDB_C009046	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A041299	PGDB_C009040	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A043509	PGDB_C009048	PGDB_AS001130	View
IC50	-	=	10-100	uM	-	—	CRBN	CRBN	-	PGDB_A046935	PGDB_C009050	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A047564	PGDB_C009061	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A048235	PGDB_C009058	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A048466	PGDB_C009042	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A050333	PGDB_C009041	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A053077	PGDB_C009044	PGDB_AS001130	View
IC50	-	<	1	uM	-	—	CRBN	CRBN	-	PGDB_A053431	PGDB_C009052	PGDB_AS001130	View

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