Activity record

PGDB_A012586

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 60-70 %

TargetIKZF3
Cell lineMM.1S
Concentration10 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS002484
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024521
Compound IDPGDB_C024521
CompoundGT-10619
Source record IDPGDB_C024521
InChIKeyDXLYOJYEINTMIB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002484
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineMM.1S
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10619

GT-10619 enlarged structureGT-10619 location on patent page 26
Activity table
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