Activity record

PGDB_A012726

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 <= 30 nM

TargetGSPT1
Cell lineCAL-51
Time6 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS002523
PatentWO2022219407A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009915
Compound IDPGDB_C009915
Compound22
Source record IDPGDB_C009915
InChIKeyYCGUEWFZTLXJMP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002523
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2022219407A1
Compound location

22

22 enlarged structure22 location on patent page 119
Activity table
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