Activity record

PGDB_A013006

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 1200-1900 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS000845
PatentWO2022219407A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009942
Compound IDPGDB_C009942
Compound9
Source record IDPGDB_C009942
InChIKeyUHZFEFIMOTUMFD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000845
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219407A1
Compound location

9

9 enlarged structure9 location on patent page 118
Activity table
Page 181 · table start
Page 182 · table end