Assay

PGDB_AS000845

System: biochemicalTarget: CRBN
Assay context summary

Assay context

66 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Technologyfluorescence
Activity compounds and values

Activity records

66 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C009949
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A007192PGDB_C009949PGDB_AS000845View
2D structure for PGDB_C009943
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A007717PGDB_C009943PGDB_AS000845View
2D structure for PGDB_C009920
IC50-<=600nM-—CRBNCRBN-WO2022219407A1PGDB_A009800PGDB_C009920PGDB_AS000845View
2D structure for PGDB_C009908
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A010119PGDB_C009908PGDB_AS000845View
2D structure for PGDB_C009913
IC50-=600-1200nM-—CRBNCRBN-WO2022219407A1PGDB_A011008PGDB_C009913PGDB_AS000845View
2D structure for PGDB_C009945
IC50-=1200-1900nM-—CRBNCRBN-WO2022219407A1PGDB_A011126PGDB_C009945PGDB_AS000845View
2D structure for PGDB_C009942
IC50-=1200-1900nM-—CRBNCRBN-WO2022219407A1PGDB_A013006PGDB_C009942PGDB_AS000845View
2D structure for PGDB_C009940
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A013360PGDB_C009940PGDB_AS000845View
2D structure for PGDB_C009962
IC50-<=600nM-—CRBNCRBN-WO2022219407A1PGDB_A014224PGDB_C009962PGDB_AS000845View
2D structure for PGDB_C009955
IC50-=1200-1900nM-—CRBNCRBN-WO2022219407A1PGDB_A015848PGDB_C009955PGDB_AS000845View
2D structure for PGDB_C009914
IC50-<=600nM-—CRBNCRBN-WO2022219407A1PGDB_A015868PGDB_C009914PGDB_AS000845View
2D structure for PGDB_C009944
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A018669PGDB_C009944PGDB_AS000845View
2D structure for PGDB_C009933
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A019161PGDB_C009933PGDB_AS000845View
2D structure for PGDB_C009916
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A019613PGDB_C009916PGDB_AS000845View
2D structure for PGDB_C009959
IC50-<=600nM-—CRBNCRBN-WO2022219407A1PGDB_A019643PGDB_C009959PGDB_AS000845View
2D structure for PGDB_C009941
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A019661PGDB_C009941PGDB_AS000845View
2D structure for PGDB_C009928
IC50->1900nM-—CRBNCRBN-WO2022219407A1PGDB_A024759PGDB_C009928PGDB_AS000845View
2D structure for PGDB_C009954
IC50-=600-1200nM-—CRBNCRBN-WO2022219407A1PGDB_A027289PGDB_C009954PGDB_AS000845View
2D structure for PGDB_C009967
IC50-<=600nM-—CRBNCRBN-WO2022219407A1PGDB_A030599PGDB_C009967PGDB_AS000845View
2D structure for PGDB_C009971
IC50-<=600nM-—CRBNCRBN-WO2022219407A1PGDB_A031136PGDB_C009971PGDB_AS000845View
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