Activity record

PGDB_A013769

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 = 30-300 nM

TargetGSPT1
Cell lineCAL-51
Time6 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS002523
PatentWO2022219407A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009909
Compound IDPGDB_C009909
Compound4
Source record IDPGDB_C009909
InChIKeyNLZDCOXIRKSMLI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002523
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2022219407A1
Compound location

4

4 enlarged structure4 location on patent page 118
Activity table
Page 184 · table start
Page 185 · table end