Activity record

PGDB_A014224

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 <= 600 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS000845
PatentWO2022219407A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009962
Compound IDPGDB_C009962
Compound73.0
Source record IDPGDB_C009962
InChIKeyYWEPIHYNBGHYGJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000845
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219407A1
Compound location

73.0

73.0 enlarged structure73.0 location on patent page 122
Activity table
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