Activity record

PGDB_A014396

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 10-20 %

TargetIKZF3
Cell lineCFPAC-1
Concentration10 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS000245
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024553
Compound IDPGDB_C024553
CompoundGT-06543
Source record IDPGDB_C024553
InChIKeyNHZHXMOJFAGKHC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000245
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineCFPAC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-06543

GT-06543 enlarged structureGT-06543 location on patent page 21
Activity table
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