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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A014505

Assay: % DegradationQC: standardized

Activity overview

Dmax = 76.6 %

Cell lineNCI-H929

ConcentrationConcentration series: 1600 nM, 400 nM, 100 nM, 25 nM, 6.25 nM, 1.56 nM, 0.39 nM, 0.1 nM

Time24 h

Assay / ReadoutWestern_blot / Dmax

Assay IDPGDB_AS002256

PatentEP4685141A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C025599

Compound实施例 3

Source record IDPGDB_C025599

InChIKeyYLCJYOJHWXPXFD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002256

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

TechnologyWestern_blot

ConcentrationConcentration series: 1600 nM, 400 nM, 100 nM, 25 nM, 6.25 nM, 1.56 nM, 0.39 nM, 0.1 nM

Treatment time24 h

Detection targetprotein_degradation

E3Not specified

Cell lineNCI-H929

OrganismHomo sapiens

Source evidence

Patent IDEP4685141A1

Compound location

实施例 3

实施例 3 enlarged structure

实施例 3 location on patent page 43

Activity table

Page 67 · table start

Page 68 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

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0 countries/regions

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SIMM · NJU