Activity record

PGDB_A014887

Assay: biochemicalTarget: CRBNQC: ambiguous
Activity overview

IC50 = 0.011 uM

TargetCRBN
E3 ligaseCRBN
Time30 min
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS000060
PatentAU2024222626A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C006039
Compound IDPGDB_C006039
CompoundB5
Source record IDPGDB_C006039
InChIKeyUOVHQZDWPNUDGN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000060
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time30 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDAU2024222626A1
Compound location

B5

B5 enlarged structureB5 location on patent page 16
Activity table
Page 17 · table single