Activity record

PGDB_A015797

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

Dmax = 6.9 %

TargetGSPT1
Cell lineHEK293
Time24 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001842
PatentWO2025090727A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010141
Compound IDPGDB_C010141
Compound8;8;8;8;8;8;8;8;8;8;8;8;8;8
Source record IDPGDB_C010141
InChIKeyDYUMYEGVQNMNAQ-MGTGFPAYSA-N

Assay context

Assay IDPGDB_AS001842
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time24 h
TargetGSPT1
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2025090727A1
Compound location

8;8;8;8;8;8;8;8;8;8;8;8;8;8

8;8;8;8;8;8;8;8;8;8;8;8;8;8 enlarged structure8;8;8;8;8;8;8;8;8;8;8;8;8;8 location on patent page 3
Activity table
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