Activity record

PGDB_A015826

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

degradation = 69 %

TargetIKZF1
ConcentrationConcentration context: titrated doses of compound
Time24 h
Assay / Readoutflow_cytometry / % Degradation
Assay IDPGDB_AS001917
PatentCN121368591A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007371
Compound IDPGDB_C007371
CompoundEXAMPLE 1
Source record IDPGDB_C007371
InChIKeyXANNILIJHXIGQL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001917
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyflow_cytometry
ConcentrationConcentration context: titrated doses of compound
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121368591A
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 68
Activity table
Page 82 · table single