Activity record

PGDB_A017415

Assay: % DegradationTarget: IKZF2QC: standardized
Activity overview

degradation = 33.5 %

TargetIKZF2
Cell lineHEK293T
Concentration1 uM
Time24 h
Assay / Readoutfluorescence / % Degradation
Assay IDPGDB_AS002485
PatentCN117836288A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000384
Compound IDPGDB_C000384
Compound14
Source record IDPGDB_C000384
InChIKeyDQYZQRGRHXEYPT-DSNGMDLFSA-N

Assay context

Assay IDPGDB_AS002485
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyfluorescence
Concentration1 uM
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
Cell lineHEK293T

Source evidence

Patent IDCN117836288A
Compound location

14

14 enlarged structure14 location on patent page 36
Activity table
Page 159 · table single