Activity record

PGDB_A018025

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 > 500 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS000094
PatentWO2024015565A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001479
Compound IDPGDB_C001479
Compound145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145
Source record IDPGDB_C001479
InChIKeyHNTGMIGBGVFOBT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000094
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2024015565A1
Compound location

145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145

145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145 enlarged structure145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145;145 location on patent page 4
Activity table
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