Activity record

PGDB_A018248

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 90-100 %

TargetIKZF3
Cell lineMOLT-4
Concentration500 nM
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS001429
PatentWO2025016359A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019524
Compound IDPGDB_C019524
CompoundGT-08003
Source record IDPGDB_C019524
InChIKeySMPXJTALQPIZLO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001429
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration500 nM
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineMOLT-4
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-08003

GT-08003 enlarged structureGT-08003 location on patent page 56
Activity table
Page 199 · table single