Activity record

PGDB_A019149

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

DC50 = 193 nM

TargetIKZF3
Time24 h
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS002428
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010127
Compound IDPGDB_C010127
CompoundEXAMPLE 3
Source record IDPGDB_C010127
InChIKeyHJXWHSJHAJGNDJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002428
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF3
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

EXAMPLE 3

EXAMPLE 3 enlarged structureEXAMPLE 3 location on patent page 90
Activity table
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