Activity record

PGDB_A019321

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 <= 20 nM

TargetGSPT1
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001361
PatentCN120441535A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001526
Compound IDPGDB_C001526
Compound3;实施例3
Source record IDPGDB_C001526
InChIKeyQDPHREAZFBQPGD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001361
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDCN120441535A
Compound location

3;实施例3

3;实施例3 enlarged structure3;实施例3 location on patent page 49
Activity table
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