Activity record

PGDB_A019643

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 <= 600 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS000845
PatentWO2022219407A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009959
Compound IDPGDB_C009959
Compound58.0
Source record IDPGDB_C009959
InChIKeyLUJIEROYLWZKTP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000845
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219407A1
Compound location

58.0

58.0 enlarged structure58.0 location on patent page 121
Activity table
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