Activity record

PGDB_A020908

Assay: % DegradationQC: standardized
Activity overview

degradation = 30-70 %

Cell lineJHH7
Concentration1 uM
Time6 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS001005
PatentCN120303269A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024154
Compound IDPGDB_C024154
CompoundExample 445
Source record IDPGDB_C024154
InChIKeySDBDXMQFGNEVKU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001005
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
Concentration1 uM
Treatment time6 h
Detection targetprotein_degradation
E3Not specified
Cell lineJHH7
OrganismHomo sapiens

Source evidence

Patent IDCN120303269A
Compound location

Example 445

Example 445 enlarged structureExample 445 location on patent page 309
Activity table
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