PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN120303269A

AssigneeShanghai Dage Biomedical Technology

TitleCompounds for Modulating HUR (ELAVL1)

Family ID89662042

Family members8

Filing year2023

Publication date2025-07-11

JurisdictionCN

Compounds342

Activity records359

Assays4

Activity compounds and values

Activity records

359 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A007378	PGDB_C023945	PGDB_AS000086	View
% Degradation	-	<	10	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A007647	PGDB_C023865	PGDB_AS000086	View
IC30	-	<=	200	nM	-	—	-	-	-	PGDB_A008047	PGDB_C023833	PGDB_AS002055	View
% Degradation	-	<	10	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A008169	PGDB_C024065	PGDB_AS000086	View
% Degradation	-	<	10	%	1 uM	6 h	-	-	JHH7	PGDB_A008238	PGDB_C024087	PGDB_AS002006	View
% Degradation	-	>	90	%	1 uM	6 h	-	-	JHH7	PGDB_A008300	PGDB_C024124	PGDB_AS001005	View
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A008455	PGDB_C023991	PGDB_AS000086	View
% Degradation	-	<	10	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A008658	PGDB_C024041	PGDB_AS000086	View
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A009148	PGDB_C024026	PGDB_AS000086	View
% Degradation	-	<	10	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A009439	PGDB_C024034	PGDB_AS000086	View
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A009767	PGDB_C023938	PGDB_AS000086	View
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A009789	PGDB_C023992	PGDB_AS000086	View
% Degradation	-	<	10	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A009826	PGDB_C024066	PGDB_AS000086	View
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A009865	PGDB_C023930	PGDB_AS000086	View
% Degradation	-	<	10	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A009881	PGDB_C024073	PGDB_AS000086	View
% Degradation	-	<	10	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A010207	PGDB_C024057	PGDB_AS000086	View
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A010385	PGDB_C023869	PGDB_AS000086	View
% Degradation	-	>=	70	%	0.1 uM	6 h	ELAVL1	-	KP4	PGDB_A010389	PGDB_C024010	PGDB_AS000086	View
% Degradation	-	>	90	%	1 uM	6 h	-	-	JHH7	PGDB_A011050	PGDB_C024119	PGDB_AS001005	View
% Degradation	-	<	10	%	1 uM	6 h	-	-	JHH7	PGDB_A011094	PGDB_C024092	PGDB_AS002006	View

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