Activity record

PGDB_A022155

Assay: % DegradationQC: standardized
Activity overview

IC50 = 0.11 uM

Cell lineMV-4-11
Time7 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001761
PatentWO2020064002A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004151
Compound IDPGDB_C004151
Compound22;22;22
Source record IDPGDB_C021453
InChIKeyHRULILFDSCOWEQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001761
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time7 d
Detection target% Cell viability
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDWO2020064002A1
Compound location

22;22;22

22;22;22 enlarged structure22;22;22 location on patent page 34
Activity table
Page 198 · table single