Activity record

PGDB_A023049

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 36 nM

TargetIKZF2
Time13 d
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001515
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010133
Compound IDPGDB_C010133
Compound4
Source record IDPGDB_C010133
InChIKeyIPPKELHFNVYXKG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001515
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time13 d
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

4

4 enlarged structure4 location on patent page 83
Activity table
Page 93 · table single