Activity record

PGDB_A023745

Assay: biochemicalTarget: KRASQC: standardized
Activity overview

IC50 = 15.28 nM

TargetKRAS
Time1.5 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000377
PatentCN121181579A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011587
Compound IDPGDB_C011587
Compound参比化合物1
Source record IDPGDB_C024582
InChIKeyFVICRBSEYSHKFY-JYQNNKODSA-N

Assay context

Assay IDPGDB_AS000377
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time1.5 h
TargetKRAS
E3Not specified

Source evidence

Patent IDCN121181579A
Compound location

参比化合物1

参比化合物1 enlarged structure参比化合物1 location on patent page 140
Activity table
Page 145 · table single