PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN121181579A

AssigneeSunrise Oncology Hong Kong

TitleMacrocyclic compound, synthesis method therefor and use thereof

Family ID98212425

Family members2

Filing year2025

Publication date2025-12-26

JurisdictionCN

Compounds99

Activity records447

Assays12

Activity compounds and values

Activity records

447 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	<=	10	nM	-	—	KRAS	-	AGS	PGDB_A007215	PGDB_C024627	PGDB_AS000586	View
IC50	-	>	1000	nM	-	—	BRAF	-	A375	PGDB_A007274	PGDB_C011587	PGDB_AS002189	View
IC50	-	<=	10	nM	-	—	KRAS	-	AsPC-1	PGDB_A007286	PGDB_C024629	PGDB_AS001095	View
IC50	-	<=	10	nM	-	—	KRAS	-	NCI-H358	PGDB_A007350	PGDB_C024609	PGDB_AS000504	View
IC50	-	<=	10	nM	-	—	KRAS	-	AsPC-1	PGDB_A007399	PGDB_C024645	PGDB_AS001095	View
IC50	-	<=	10	nM	-	—	KRAS	-	AsPC-1	PGDB_A007544	PGDB_C024652	PGDB_AS001095	View
IC50	-	<=	10	nM	-	—	KRAS	-	AsPC-1	PGDB_A007748	PGDB_C024621	PGDB_AS001095	View
IC50	-	<=	10	nM	-	—	-	-	MIA PaCa-2	PGDB_A007765	PGDB_C024602	PGDB_AS001225	View
IC50	-	=	100-1000	nM	-	—	KRAS	-	AGS	PGDB_A007807	PGDB_C024611	PGDB_AS000586	View
IC50	-	<=	10	nM	-	—	KRAS	-	HPAC	PGDB_A007811	PGDB_C024622	PGDB_AS000097	View
IC50	-	<=	10	nM	-	—	KRAS	-	HPAC	PGDB_A007898	PGDB_C024680	PGDB_AS000097	View
IC50	-	<=	10	nM	-	—	KRAS	-	HPAC	PGDB_A007931	PGDB_C024679	PGDB_AS000097	View
IC50	-	<=	10	nM	-	—	KRAS	-	HPAC	PGDB_A007999	PGDB_C024642	PGDB_AS000097	View
IC50	-	=	10-100	nM	-	—	KRAS	-	AsPC-1	PGDB_A008380	PGDB_C024590	PGDB_AS001095	View
IC50	-	>	1000	nM	-	—	BRAF	-	A375	PGDB_A008504	PGDB_C024673	PGDB_AS002189	View
IC50	-	<=	10	nM	-	—	KRAS	-	AGS	PGDB_A008544	PGDB_C024644	PGDB_AS000586	View
IC50	-	<=	10	nM	-	—	KRAS	-	AsPC-1	PGDB_A008903	PGDB_C024593	PGDB_AS001095	View
IC50	-	<=	10	nM	-	—	KRAS	-	AGS	PGDB_A009029	PGDB_C024646	PGDB_AS000586	View
IC50	-	=	10-100	nM	-	—	KRAS	-	AsPC-1	PGDB_A009090	PGDB_C024614	PGDB_AS001095	View
IC50	-	<=	10	nM	-	—	KRAS	-	HPAC	PGDB_A009135	PGDB_C024624	PGDB_AS000097	View

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