Activity record

PGDB_A023826

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 0.0001-0.01 uM

TargetGSPT1
E3 ligaseCRBN
Cell lineKG-1
Time72 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001194
PatentCN118234721A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019811
Compound IDPGDB_C019811
Compound化合物25
Source record IDPGDB_C001223
InChIKeyMSKBGEXJQCMHCO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001194
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time72 h
TargetGSPT1
E3CRBN
Cell lineKG-1

Source evidence

Patent IDCN118234721A
Compound location

化合物25

化合物25 enlarged structure化合物25 location on patent page 31
Activity table
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