Activity record

PGDB_A024177

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

Dmax = 33.5 %

TargetGSPT1
Cell lineNCI-H1155
Time72 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS001612
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002846
Compound IDPGDB_C002846
Compound95;95;95
Source record IDPGDB_C002846
InChIKeyNBFAWLWAYOGJOI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001612
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time72 h
TargetGSPT1
E3Not specified
Cell lineNCI-H1155
OrganismHomo sapiens

Source evidence

Patent IDWO2024059107A1
Compound location

95;95;95

95;95;95 enlarged structure95;95;95 location on patent page 12
Activity table
Page 142 · table single