Activity record

PGDB_A024517

Assay: % DegradationTarget: VCLQC: standardized
Activity overview

DC50 = 116 nM

TargetVCL
Cell lineBE2C
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS002418
PatentWO2025199151A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011574
Compound IDPGDB_C011574
Compound5
Source record IDPGDB_C011574
InChIKeyCDHXZRFMQGMOLJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002418
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetVCL
E3Not specified
Cell lineBE2C
OrganismHomo sapiens

Source evidence

Patent IDWO2025199151A1
Compound location

5

5 enlarged structure5 location on patent page 118
Activity table
Page 132 · table start
Page 133 · table end