Activity record

PGDB_A024779

Assay: % DegradationTarget: CCNKQC: ambiguous
Activity overview

DC50 < 500 nM

TargetCCNK
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001864
PatentWO2025245472A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C012031
Compound IDPGDB_C012031
Compound167
Source record IDPGDB_C012031
InChIKeyUYEJMFIPRWBJNL-HOTGVXAUSA-N

Assay context

Assay IDPGDB_AS001864
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
Detection targetprotein_degradation
TargetCCNK
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025245472A1
Compound location

167

167 enlarged structure167 location on patent page 80
Activity table
Page 217 · table start
Page 218 · table end