Activity record

PGDB_A025453

Assay: % DegradationTarget: ESR1QC: ambiguous
Activity overview

degradation = 97 %

TargetESR1
Cell lineMCF-7
ConcentrationConcentration context: 5.12x10⁻¹² M, 5.12x10⁻¹³ M
Time4 h
Assay / Readoutrelative_activity_percent / % Degradation
Assay IDPGDB_AS002178
PatentRU2847441C1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008965
Compound IDPGDB_C008965
Compound实施例2
Source record IDPGDB_C008965
InChIKeyKJAAPZIFCQQQKX-MUUNZHRXSA-N

Assay context

Assay IDPGDB_AS002178
Assay family% Degradation
Assay systemcell_based
Readoutrelative_activity_percent
ConcentrationConcentration context: 5.12x10⁻¹² M, 5.12x10⁻¹³ M
Treatment time4 h
TargetESR1
E3Not specified
Cell lineMCF-7
OrganismHomo sapiens

Source evidence

Patent IDRU2847441C1
Compound location

实施例2

实施例2 enlarged structure实施例2 location on patent page 62
Activity table
Page 67 · table single