Activity record

PGDB_A025818

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

degradation <= 25 %

TargetIKZF3
Cell lineNCI-H929
Concentration20 uM
Time24 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS001550
PatentAU2020392427A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019040
Compound IDPGDB_C019040
Compound30;30;30
Source record IDPGDB_C019021
InChIKeyICFGGDWIKQYLQN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001550
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
Concentration20 uM
Treatment time24 h
Detection targetprotein_degradation
TargetIKZF3
E3Not specified
Cell lineNCI-H929
OrganismHomo sapiens

Source evidence

Patent IDAU2020392427A1
Compound location

30;30;30

30;30;30 enlarged structure30;30;30 location on patent page 38
Activity table
Page 114 · table single