Activity record

PGDB_A025826

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

DC50 = 1.1-1.4 nM

TargetIKZF2
Time13 d
Assay / Readoutflow_cytometry / DC50
Assay IDPGDB_AS002365
PatentCN121368591A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007371
Compound IDPGDB_C007371
CompoundEXAMPLE 1
Source record IDPGDB_C007371
InChIKeyXANNILIJHXIGQL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002365
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyflow_cytometry
Treatment time13 d
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDCN121368591A
Compound location

EXAMPLE 1

EXAMPLE 1 enlarged structureEXAMPLE 1 location on patent page 68
Activity table
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