Activity record

PGDB_A025886

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 30.5 nM

TargetGSPT1
Cell lineMV-4-11
Time3 d
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS001562
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001871
Compound IDPGDB_C001871
CompoundWX001
Source record IDPGDB_C001871
InChIKeyQMFBKFUDBDPNAM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001562
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time3 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDWO2023001028A1
Compound location

WX001

WX001 enlarged structureWX001 location on patent page 13
Activity table
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