Activity record

PGDB_A026330

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 = 0.08703 uM

TargetCRBN
E3 ligaseCRBN
Time2 h
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS002039
PatentCN121378270A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007378
Compound IDPGDB_C007378
Compound实施例5
Source record IDPGDB_C007378
InChIKeyCZHFALHQAHISOD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002039
Assay familybinding
Assay systembiochemical
ReadoutIC50
Treatment time2 h
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDCN121378270A
Compound location

实施例5

实施例5 enlarged structure实施例5 location on patent page 17
Activity table
Page 20 · table single