Search Browse Statistics Contact Help

·

SIMM · NJU

Loading activity

Loading detail record from the SQLite release...

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU

Search Browse Statistics Contact Help

·

SIMM · NJU

Activity record

PGDB_A026367

Assay: % DegradationQC: standardized

Activity overview

Emax < 45 %

Cell lineKELLY.2

TimeDC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM

Assay / Readoutluminescence / Emax

Assay IDPGDB_AS000499

PatentWO2022081927A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C016636

Compound64

Source record IDPGDB_C026766

InChIKeyQHXQZHSCNCCFDJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000499

Assay family% Degradation

Assay systemcell_based

ReadoutEmax

Technologyluminescence

Treatment timeDC50 > 10000 nM | DC50 >= 100 nM and <= 1000 nM | > 100 nM

TargetSALL4

E3Not specified

Cell lineKELLY.2

Source evidence

Patent IDWO2022081927A1

Compound location

64

64 enlarged structure

64 location on patent page 530

Activity table

Page 529 · table start

Page 530 · table middle

Page 531 · table middle

Page 532 · table middle

Page 533 · table middle

Page 534 · table middle

Page 535 · table middle

Page 536 · table middle

Page 537 · table middle

Page 538 · table middle

Page 539 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU