Activity record

PGDB_A026689

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 20-30 %

TargetIKZF3
Cell lineCCRF-CEM
Concentration10 nM
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS001627
PatentWO2025016359A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019522
Compound IDPGDB_C019522
CompoundGT-07842
Source record IDPGDB_C019522
InChIKeyCFGDAMGLSMBGQF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001627
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineCCRF-CEM
OrganismHomo sapiens

Source evidence

Patent IDWO2025016359A1
Compound location

GT-07842

GT-07842 enlarged structureGT-07842 location on patent page 42
Activity table
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