Activity record

PGDB_A027533

Assay: viabilityTarget: KRASQC: standardized
Activity overview

IC50 = 0.4233 nM

TargetKRAS
Cell lineSW620
Time5 d
Assay / ReadoutCCK-8 / IC50
Assay IDPGDB_AS000800
PatentWO2025214350A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011587
Compound IDPGDB_C011587
CompoundRef.1
Source record IDPGDB_C011587
InChIKeyFVICRBSEYSHKFY-JYQNNKODSA-N

Assay context

Assay IDPGDB_AS000800
Assay familyviability
Assay systemcell_based
ReadoutIC50
TechnologyCCK-8
Treatment time5 d
Detection target% Cell viability
TargetKRAS
E3Not specified
Cell lineSW620
OrganismHomo sapiens

Source evidence

Patent IDWO2025214350A1
Compound location

Ref.1

Ref.1 enlarged structureRef.1 location on patent page 220
Activity table
Page 226 · table single