Activity record

PGDB_A028188

Assay: % DegradationTarget: CCNKQC: ambiguous
Activity overview

DC50 > 2000 nM

TargetCCNK
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001864
PatentWO2025245472A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C012000
Compound IDPGDB_C012000
Compound135;135
Source record IDPGDB_C012000
InChIKeyYSVVLXMBCYDUNA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001864
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
Detection targetprotein_degradation
TargetCCNK
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025245472A1
Compound location

135;135

135;135 enlarged structure135;135 location on patent page 77
Activity table
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