Activity record

PGDB_A028788

Assay: viabilityTarget: IKZF3QC: standardized
Activity overview

inhibition = 10-20 %

TargetIKZF3
Cell lineMM.1S
Concentration10 nM
Time96 h
Assay / Readout% Inhibition / viability
Assay IDPGDB_AS002484
PatentWO2025162225A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024576
Compound IDPGDB_C024576
CompoundGT-10319
Source record IDPGDB_C024576
InChIKeyWWYVFJREDZWQLD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002484
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Concentration10 nM
Treatment time96 h
Detection target% Cell viability
TargetIKZF3
E3Not specified
Cell lineMM.1S
OrganismHomo sapiens

Source evidence

Patent IDWO2025162225A1
Compound location

GT-10319

GT-10319 enlarged structureGT-10319 location on patent page 38
Activity table
Page 155 · table single