Activity record

PGDB_A029509

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

DC50 = 74.9 nM

TargetGSPT1
Cell lineCAL-51
Time6 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS001139
PatentCN119264113A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000674
Compound IDPGDB_C000674
Compound化合物 4;化合物 4
Source record IDPGDB_C000674
InChIKeyBZWFZAIILQPVRS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001139
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time6 h
Detection targetprotein_degradation
TargetGSPT1
E3Not specified
Cell lineCAL-51

Source evidence

Patent IDCN119264113A
Compound location

化合物 4;化合物 4

化合物 4;化合物 4 enlarged structure化合物 4;化合物 4 location on patent page 4
Activity table
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