PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN119264113A

AssigneeJiangsu Institute Of Sports Health

TitleGSPT1 degradation agent and its application

Family ID94108381

Family members1

Filing year2024

Publication date2025-01-07

JurisdictionCN

Compounds5

Activity records20

Assays4

Activity compounds and values

Activity records

20 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	=	16	nM	-	—	GSPT1	-	ABC-1	PGDB_A007955	PGDB_C000673	PGDB_AS001474	View
DC50	-	=	16	nM	-	—	GSPT1	-	ABC-1	PGDB_A016249	PGDB_C000672	PGDB_AS001474	View
DC50	-	=	46.7	nM	-	—	GSPT1	-	CAL-51	PGDB_A017738	PGDB_C000672	PGDB_AS001139	View
IC50	-	>	1000	nM	-	—	GSPT1	-	CAL-51	PGDB_A019641	PGDB_C000675	PGDB_AS001498	View
DC50	-	=	74.9	nM	-	—	GSPT1	-	CAL-51	PGDB_A029509	PGDB_C000674	PGDB_AS001139	View
DC50	-	=	170.8	nM	-	—	GSPT1	-	ABC-1	PGDB_A042982	PGDB_C000671	PGDB_AS001474	View
IC50	-	=	8.4	nM	-	—	GSPT1	-	CAL-51	PGDB_A044099	PGDB_C000672	PGDB_AS001498	View
IC50	-	=	10.5	nM	-	—	GSPT1	-	ABC-1	PGDB_A052785	PGDB_C000674	PGDB_AS002488	View
DC50	-	=	178	nM	-	—	GSPT1	-	ABC-1	PGDB_A053046	PGDB_C000675	PGDB_AS001474	View
DC50	-	=	16	nM	-	—	GSPT1	-	CAL-51	PGDB_A055780	PGDB_C000673	PGDB_AS001139	View
IC50	-	=	28	nM	-	—	GSPT1	-	ABC-1	PGDB_A056585	PGDB_C000675	PGDB_AS002488	View
IC50	-	=	0.5	nM	-	—	GSPT1	-	ABC-1	PGDB_A056672	PGDB_C000672	PGDB_AS002488	View
IC50	-	=	68.9	nM	-	—	GSPT1	-	CAL-51	PGDB_A061884	PGDB_C000671	PGDB_AS001498	View
DC50	-	=	76.09	nM	-	—	GSPT1	-	ABC-1	PGDB_A063374	PGDB_C000674	PGDB_AS001474	View
IC50	-	=	10	nM	-	—	GSPT1	-	CAL-51	PGDB_A064049	PGDB_C000673	PGDB_AS001498	View
DC50	-	=	219.2	nM	-	—	GSPT1	-	CAL-51	PGDB_A064642	PGDB_C000671	PGDB_AS001139	View
DC50	-	>	1000	nM	-	—	GSPT1	-	CAL-51	PGDB_A068423	PGDB_C000675	PGDB_AS001139	View
IC50	-	=	0.7	nM	-	—	GSPT1	-	ABC-1	PGDB_A071837	PGDB_C000673	PGDB_AS002488	View
IC50	-	=	24.6	nM	-	—	GSPT1	-	CAL-51	PGDB_A072217	PGDB_C000674	PGDB_AS001498	View
IC50	-	=	10	nM	-	—	GSPT1	-	ABC-1	PGDB_A076149	PGDB_C000671	PGDB_AS002488	View

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